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Kao Confirms Physiological and Psychological Effects of Touching Clean Hair

 Kao examined the physiological (oxytocin) and psychological (emotions and self-awareness) effects of touching clean hair. I found that my sense of affirmation increased. To date, the company has reported that feeling the texture of hair increases positive emotions, which may affect self-awareness and beauty behavior, but the act of touching hair also changes physiologically. It was unclear whether the Therefore, this time, we focused on "oxytocin" as a biological response index that captures physiological changes, washed, treated, and styled 11 women's hair, and investigated whether the amount of oxytocin in saliva changed before and after touching. At the same time, we asked them to evaluate the state of their hair when they touched it from 10 points of view, and evaluated the emotions and self-consciousness that occurred at that time. First, we examined the relationship between changes in the amount of oxytocin in saliva and the evaluation of each item regarding the co...

Joint paper with POLA Kasei and the University of Tokyo published in academic journal "Cell Reports"

 POLA CHEMICAL INDUSTRIES conducted joint research with the Institute of Industrial Science, the University of Tokyo on the relationship between skin blemishes and nerves, and in 2021 showed the involvement of nerves in blemishes, following the results published in the Journal of Dermatological Science. Recently, we succeeded in elucidating the mechanism, and a paper was published in "Cell Reports," a sister journal of the world-renowned international scientific journal "Cell." We will continue to pursue innovative research and aim to provide products that provide surprises and excitement. The title of the paper is "Human Sensory Neurons Modulate Melanocytes Through Secretion of RGMB", and the results will be used to understand localized skin pigmentation such as age spots and develop improvement methods. It was known that blemishes tend to occur in certain areas of human skin, but the reasons for this were unknown. On the other hand, it was known that sen...

China's National Drug Administration has approved "Cosmetics New Ingredients," which is the third Japanese company under the China Cosmetics New Ingredients Registration System.

 Based on the new "Cosmetics Supervision Ordinance", which was completely revised last year for the first time in 31 years, and the related practical ordinance "Regulations for managing application materials for registration of new cosmetic raw materials," Worldwide IP Consulting Japan Co., Ltd. The registration procedures for new cosmetic raw materials entrusted by the company were applied to the China National Drug Administration, approved on September 17, 2022, and announced on the official website of NMPA. As of September 17, 2022, there are 38 new raw material registration approvals announced, 25 of which are by Chinese companies and 13 by foreign companies. This is the third Japanese company to receive approval, following Shiseido Co., Ltd. and ADEKA Co., Ltd. [Issues faced by Japanese companies - sometimes forced to give up business] In order to distribute cosmetics in the market in China, it is necessary to register and apply for registration of cosmetic pro...

Low-dose isotretinoin does not affect ovarian reserve

 Isotretinoin, one of the most frequently used drugs in routine dermatological practice, has been raised for teratogenicity with a black box warning. The aim of the current study was to evaluate the effect of low-dose isotretinoin on ovarian reserve in women with moderate to severe acne. A 6-month prospective controlled cohort study of 60 female acne patients and 66 controls receiving low-dose isotretinoin. Effects on ovarian reserve were evaluated by anti-Müllerian hormone, ovarian volume, and antral follicle count. As a result, there was no significant difference in serum anti-Mullerian hormone levels between isotretinoin-treated and control patients. In addition, there was no significant change in anti-Müllerian hormone levels before and after treatment in treated patients. Both ovarian volume and antral follicle number did not change significantly before and after treatment

Examining the relationship between obesity and dietary antioxidants

 In this noncross-sectional study, dietary content and intake were assessed using a validated food frequency questionnaire in 203 overweight/obese adolescents. We measured iron reducing antioxidant capacity (FRAP), which indicates the total antioxidant capacity of the diet, anthropometric parameters and blood pressure status, and insulin, glucose, and lipid profiles from fasting blood samples. Two different methods [modified International Diabetes Federation (IDF) criteria and insulin resistance (HOMA)] were used to classify participants as metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO). IDF criteria associated with] were applied. As a result, 79 (38.9%) were defined as MUO by the IDF criteria and 67 (33.0%) by the IDF/HOMA definition. On the IDF criteria, the highest FRAP tertile was associated with being less likely to be MUO in the maximally adjusted model compared to the lowest tertile. However, the IDF/HOMA-IR criteria showed no significant relationsh...

Seiwa Kasei Develops New Hair Care Ingredients Derived from Soybeans

 Seiwa Kasei, a research and development manufacturer of raw materials for cosmetics and quasi-drugs, has developed a soybean protein derivative "Soy Heat Guard" (product name: Promois WS) as a new hair care ingredient from the protein hydrolyzate "Promois" series. -HSIGPD) has been successfully developed and sales have started in June this year. "Soy Heat Guard" is a functional hair care ingredient that has been confirmed to react to the heat of dryers and curling irons and coat each strand of hair, leading to beautiful hair (Heat Active Mechanism). An increasing number of people are concerned about hair damage caused by the heat of hair dryers and curling irons used for hair drying and styling, and the demand for care products such as out-of-bath treatments and hair oils is increasing.

Yamakawa Trading proposes effective natural ingredients for pore care

 Yamakawa Trading, which has a trading company function centered on European raw material manufacturers, proposes "PORE-REDUCTYL NT", a COSMOS-approved raw material that uses 100% naturally derived useful ingredients. PORE-REDUCTYL NT is said to be derived from Fomes officinalis, a mushroom that grows wild in virgin forests of conifers widely distributed in North America and Europe. Also known as Agarikon (Japanese name: Ebriko), it is the most important medicinal mushroom in ancient Europe containing agaric acid, and is said to have astringent, tightening, and moisturizing effects.