Examining the relationship between obesity and dietary antioxidants

 In this noncross-sectional study, dietary content and intake were assessed using a validated food frequency questionnaire in 203 overweight/obese adolescents. We measured iron reducing antioxidant capacity (FRAP), which indicates the total antioxidant capacity of the diet, anthropometric parameters and blood pressure status, and insulin, glucose, and lipid profiles from fasting blood samples. Two different methods [modified International Diabetes Federation (IDF) criteria and insulin resistance (HOMA)] were used to classify participants as metabolically healthy obese (MHO) or metabolically unhealthy obese (MUO). IDF criteria associated with] were applied.

As a result, 79 (38.9%) were defined as MUO by the IDF criteria and 67 (33.0%) by the IDF/HOMA definition. On the IDF criteria, the highest FRAP tertile was associated with being less likely to be MUO in the maximally adjusted model compared to the lowest tertile. However, the IDF/HOMA-IR criteria showed no significant relationship between odds of FRAP and MUO after adjusting for all confounders. Although it was concluded that adolescents with higher dietary antioxidant intakes were less likely to develop MUO according to the IDF criteria, no substantial association was found with the HOMA-IR/IDF definition.

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