Japan Cosmetics News

 Shiseido utilizes its proprietary "inner and outer skin 3D elastic imaging technology". When the stratum corneum hardens, the mechanical stress applied to the dermis increases when the skin moves due to facial expressions, etc. It was confirmed that the skin gap between the layer and the dermis) progresses. In addition, it was discovered that the active ingredient "pure retinol", which has been shown to be effective in improving wrinkles, has a softening effect on the stratum corneum, revealing that it has a new function to prevent the progression of wrinkles from the surface of the skin to the depths of the skin. made it While pure retinol has a high skin-improving effect, it is easily decomposed by oxygen, heat, light, etc., so in order to fully demonstrate its effect, it is necessary to keep it stable and deliver it to the skin reliably. In the course of over 30 years of research on retinol, the company has developed a proprietary technology called "Shiseid

 Through joint research with Kirin Holdings, FANCL has discovered that "14-dehydroergosterol (14-DHE)" contained in Kirin's "white koji mold" increases the enzyme "arginase 1" involved in skin beautifying functions. It has been announced that the signs of skin aging can be improved by continuous use of a serum containing koji mold extract. This time, as a result of further elucidating the detailed mechanism of the skin beautifying function of "14-DHE" that has been confirmed so far, "14-DHE" increases arginase 1, inhibits glycation damage, and accelerates aging. It was found that suppressing this leads to anti-aging.

 Paula noted that people who are aware of the cold often suffer from menstrual cramps and irregular menstruation. found to decrease in volume. 　 From this, it is expected that reducing the decrease in ERβ expression due to low temperatures may lead to the resolution of women's worries. This knowledge will be applied to products launched by POLA. A survey conducted by the company suggested that people who are aware of the cold are more likely to experience women-specific problems such as menstrual cramps and irregular menstruation more frequently than those who are not aware of the cold. It is generally known that women's peculiar troubles are caused by short-term and long-term drastic fluctuations in the amount of estrogen, a female hormone. As a factor other than the drastic fluctuations in estrogen levels, this time we focused on ERβ, a receptor that controls the ability to receive estrogen, and studied its relationship with coldness. In order to investigate the effects of co

 Shiseido announced on June 22 that it has selected 10 recipients of the 16th Shiseido Female Researcher Science Grant. The award ceremony will be held on July 6, 2023 (Thursday) at the Shiseido Global Innovation Center, with the theme of "building a network among female researchers aiming to realize a sustainable society." Based on the idea that "supporting female researchers who will play leading roles in the next generation will lead to the development of science and technology," this grant supports a wide range of research themes in the natural sciences (science, engineering, and life sciences in general). ), since its establishment in 2007, it has provided research grants to up to 10 female researchers every year. The 1,000,000 yen subsidy given to each awardee is also flexible in terms of creating an environment that allows them to balance research activities with life events such as childbirth and childcare (e.g. childcare expenses when attending academic con

 We evaluated the effectiveness of an anti-aging gel containing eicosapentaenoic acid (EPA) and cannabidiol (CBD) in preventing and treating skin aging. Skin aging is a complex process influenced by various factors such as UV radiation, air pollution and malnutrition. This study aimed to evaluate the compatibility and efficacy of EPA and CBD in skin anti-aging by in vitro, ex vivo, and clinical evaluations. The results showed that EPA enhanced the protective effects of CBD by reducing the secretion of inflammatory substances associated with photoaging, namely prostaglandin E2 (PGE2) and interleukin-8 (IL-8). Histological examination also observed a positive effect of this gel on extracellular matrix (ECM) remodeling after UV irradiation. In clinical studies (33 subjects), this gel demonstrated significant improvement in various signs of aging. A reduction in the area and volume of wrinkles at the corners of the eyes and a reduction in the volume of fine wrinkles were confirmed. The gel

 The results of a cross-sectional study that examined the frequency of staple foods and the relationship between skipping meals and metabolic syndrome in Korean adults have been published. Previously published papers point out that eating less frequently may increase the risk of metabolic syndrome. In this study, we analyzed data from 22,699 adults from the 2016-2020 Korean National Health and Nutrition Survey, and investigated the association between staple meal frequency and skipping meals and metabolic syndrome. Men who ate two meals a day were more likely to develop metabolic syndrome than men who ate three meals a day (odds ratio 1.16). Women who ate two meals a day and skipped breakfast were more likely to have elevated fasting blood glucose (odds ratio 1.18) and triglycerides (odds ratio 1.19). On the other hand, women who skipped dinner were less likely to have elevated fasting blood glucose levels (odds ratio 0.74). The researchers said meal frequency and skipped meals may be