Fungi linked to etiology of acne vulgaris

 A prospective case-control study was conducted in 100 people with acne vulgaris and 100 people without acne vulgaris. Direct microscopy and culture of the samples were performed according to the standards of the Clinical and Laboratory Standards Institute. Descriptive analysis, independent sample t-test, and chi-square test were used for statistical analysis. Subjects in the control group were paired with acne vulgaris patients by age and sex.


As a result, direct microscopic examination revealed hyphae in samples from all subjects with acne and in samples from four healthy controls. Cultures in 18 people with acne vulgaris were positive for Aspergillus in 6, Penicillium in 7, Cladosporium in 3, Candida in 1, and Acremonium in 1. rice field. In addition, Candida was observed in 2 healthy individuals in the control group. Our results indicate that fungi may be involved in the etiology of acne vulgaris.

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