Confirmed antibacterial action of sophorolipid and palmarosa compound

 The antibacterial activity of sophorolipid and palmarosa oil and their combined effects were evaluated by the trace liquid dilution method and the checkerboard method. Antioxidant activity was measured by the DPPH method.


As a result, it was confirmed that this compound exhibits antibacterial activity against Staphylococcus aureus and Staphylococcus epidermidis. The combination of sophorolipids and palmarosa oil resulted in synergistic and additive interactions, reducing the concentrations required for efficacy against Staphylococcus aureus and Staphylococcus epidermidis to 98.4% and 50%, respectively. Cosmetic formulations without chemical preservatives showed antibacterial activity against Staphylococcus aureus, Staphylococcus epidermidis, and P. acnes. The pH value and sensory properties of the pharmaceutical product were stable under all the conditions tested. This study has shown the potential for the development of effective multifunctional cosmetic formulations containing natural preservatives for the treatment of acne vulgaris and other skin infections.

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