Shiseido confirms improvement of skin transparency by combined use of oral preparation and application formulation

 Shiseido has found that the leaves of Moringa oleifera have the effect of promoting the production of glutathione, which has a high antioxidant effect, and the effect of suppressing the production of melanin.

Furthermore, by using an oral preparation containing wasabi noki leaf and pineapple extract, etc., and a coating product containing the in-house developed ingredients potassium 4-methoxyate and tranexamic acid, the product is compared with the case of single use. It was confirmed that the brightness and transparency of the skin were further enhanced.

This research was carried out with the approach of Inside / Outside of the original R & D philosophy "DYNAMIC HARMONY".

Combining care from the inside of the body by ingesting oral preparations and care from the outside of the body by applying the drug, we will promote the development of a new holistic approach that works on the health of the whole body and the beauty of the skin.

The company has been developing various ingredients, verifying their effects, and developing products using useful ingredients, while making use of the knowledge of dermatology and material science, which are the research areas of strength. Also. He has been paying attention to research in the field of beauty and wellness from early on, and has been engaged in research on supplements and foods that support beauty from the inside of the body for many years, and has proposed an approach that leads to beauty from inside and outside. However, in previous studies, the effect of using these in combination has not been sufficiently confirmed.

Therefore, in addition to searching for new ingredients that are useful for the skin, we investigated the effects of using oral preparations and application formulations together.

This time, taking advantage of the findings so far that we have searched for ingredients that have the effect of suppressing skin erythema and blackening due to ultraviolet rays, we have newly developed strong antioxidant power on wasabi tree leaves through joint research with Professor Yoshinori Katakura of Kyushu University. We found the effect of promoting the production of glutathione, which is a component in the body, and the effect of suppressing the production of melanin.

A continuous use test was carried out using an oral preparation containing wasabi tree leaves and a pineapple extract, which is also known to have a glutathione production promoting effect.

As a result, it was confirmed that the increase in skin brightness and the decrease in the amount of melanin were confirmed in the group ingesting the oral preparation with the target ingredient at the 13th week as compared with the group without the target ingredient. In addition, blood antioxidant power was measured in order to investigate the antioxidant power in the body, which is important for suppressing skin damage caused by ultraviolet rays. As a result, an increase in blood antioxidant power was observed from the 3rd week of ingestion.