Confirmed anti-photoaging effect on ginger family plants from Thailand

 Reactive oxygen species generated by exposure to ultraviolet (UVB) stimulate fibroblasts. The fibroblasts promote the production of matrix metalloproteinase-1, a degrading enzyme such as collagen and hyaluronic acid, and induce skin aging. In this study, we examined whether the ginger herbaceous plant Kyoou (and Temurawaku reduce MMP-1 expression, which is commonly used in traditional Thai women's medicines. Kyoou and Temurawaku extracts, and Using the isolated compound, a study was conducted to investigate the possibility of reducing UVB-induced MMP-1 in HaCaT keratinocytes, and the effect was evaluated by measuring the total phenol content and antioxidant capacity of the extract.

The results showed that both the two extracts and compounds effectively reduced UVB-induced MMP-1 levels in HaCaT cells and restored cell cycle arrest. In addition, the Temurawaku extract contained more phenolic components than the Curcuma cona extract, and a stronger antioxidant effect was observed. Curcuma and Temurawaku extracts have been suggested as potential alternative natural materials to prevent UVB-induced skin photoaging.

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