VC60 won the Excellent Presentation Award at the General Assembly and Academic Conference of the Japanese Society of Cosmetic Dermatology

 Vitamin C60 Bioresearch recently held 2-aza-8-oxohypoxanthine (AOH), a new cosmetic ingredient that the company is developing for practical use at the 39th Annual Meeting of the Japanese Society of Cosmetic Dermatology. ) Was presented on the results of the efficacy and safety evaluation research, and received the Excellent Presentation Award.

In 2010, Professor Hirokazu Kawagishi of Shizuoka University discovered "2-azahipoxanthin (AHX)", a substance that promotes the growth of turfgrass, from the culture solution of Lepista sordida, a type of mushroom that forms fairy rings. After that, AOH was discovered as a metabolite of imidazole-4-carboxyamide (ICA) and AHX, which suppress the growth of turfgrass.

As a result of verifying the effectiveness of AOH on the skin by DNA microarray analysis, it was found that AOH has a high possibility of strengthening and improving the skin barrier function.

In addition, when a human efficacy test (clinical test) was conducted, the water content of the stratum corneum increased by applying 0.1% AOH for 8 weeks. Furthermore, it was revealed that TEWL, which is an index showing the amount of water evaporation from the skin, decreased statistically significantly.



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